Journal of Mosquito Research 2015, Vol.5, No.14, 1-8
7
funestus
s.s is substantially more anthropophagic and
endophagic than
An. arabiensis,
this species may not
be a good candidate of zooprophylaxis.
In conclusion, the current study found increased levels
of resistance to insecticides in both Mwea and Ahero,
although resistance was much higher in Mwea. The
lower malaria parasite rates observed in both Mwea
and Ahero are consistent with the expected effectiveness
of insecticide-based intervention against malaria and
our results strongly suggest that current levels of
resistance have not compromised their effectiveness.
While epidemiological studies will be needed to
determine what resistance levels interfere with the
effectiveness of such interventions, the need for
continued monitoring of resistance so as to detect and
manage it cannot be overstated.
Competing interests:
The authors declare no competing interests.
Authors contributions
JC is the corresponding author and the main researcher of this
work.
POM participated in the critical revision of this work and
guidance in the molecular analysis.
JNM assisted in the care and use of animals in the laboratory.
LK supervised field visits, all laboratory experiments and
rearing of the
Anopheles
mosquitoes.
CM was the overall supervisor for the whole work right from
its funding to conclusion.
Acknowledgements
This work was funded by the Bill and Melinda Gates
Foundation and the World Health Organization (Grant No.
1580) and is published with the permission of the Director,
Kenya Medical Research Institute (KEMRI). Authors are
grateful to villagers and households owners in Mwea and Ahero
for consent to mosquito collection from their homesteads.
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