International Journal of Clinical Case Reports 2015, Vol.5, No. 42, 1-6
1
Research Report Open Access
Odontogenic Keratocyst: An Unusual Clinical Presentation
Agarwal N.
1
, Giri D.
2
, Sinha A.
3
, Srivastava S.
4
, Prasad R.K.
5
, Nayyar A.S.
6
1. Professor & Head, Dept of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow,
Uttar Pradesh, India
2. Post graduate student, Dept of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow,
Uttar Pradesh, India
3. Reader, Dept of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow, Uttar Pradesh,
India
4. Senior Lecturer, Dept of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow, Uttar
Pradesh, India
5. Senior Lecturer, Dept of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow, Uttar
Pradesh, India
6. Reader, Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani,
Maharashtra, India
Corresponding author email
International Journal of Clinical Case Reports, 2015, Vol.5, No.42 doi: 10.5376/ijccr.2015.05.0042
Received: 16 Sep., 2015
Accepted: 13 Oct., 2015
Published: 19 Oct., 2015
Copyright
©
2015 Agarwal et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:
Agarwal N., Giri D., Sinha A., Srivastava S., Prasad R.K. and Nayyar A.S., 2015, Odontogenic Keratocyst: An Unusual Clinical Presentation, International
Journal of Clinical Case Reports, 5(42) 1
-
6 (doi
Abstract
The odontogenic keratocyst (OKC) is a developmental cyst of the jaws of epithelial origin. This lesion is commonly found
in the ascending ramus and posterior mandible, and can become quite large due to its rapid growth and its extension into the adjacent
structures. Herein, we are reporting a case of odontogenic keratocyst involving the anterior mandible which was mimicking other
cysts and tumors which occur in that region more frequently. On closer view into the case, the lesion was proved to be an OKC. The
lesion was successfully treated by complete enucleation. Because of the uniqueness of this case, the clinical, radiological, and
histological features of this cyst/tumor are discussed in this article.
Keywords
Odontogenic Keratocyst; Odontogenic Cysts; Keratocystic Odontogenic Tumor; Mandible; Bimodal; Carnoy’s solution
Introduction
Ever since Philipsen described the odontogenic
keratocyst (OKC) in 1956, the lesion has turned into a
center of momentous clinical interest because of its
unusual growth pattern and tendency to recur even
after surgical removal (Sulabha et al., 2013). This
lesion was recently renamed by Philipsen as keratocystic
odontogenic tumour (KCOT) and reclassified as an
odontogenic neoplasm in the World Health Organization’s,
2005 edition of its histological classification of
odontogenic tumours. According to this edition, the
KCOT has been defined as a benign uni or multicystic
intraosseous tumour of odontogenic origin, with a
characteristic lining of parakeratinized stratified
squamous epithelium and potentially aggressive,
infiltrative behavior (Çakur et al., 2008; MacDonald-
Jankowski, 2011). Odontogenic Keratocyst (OKCs) of
the jaw is also recognized as a developmental cyst and
there is general agreement that the odontogenic
keratocyst arises from the cell rests of the dental
lamina. This cyst shows a different growth mechanism
and biologic behaviour unlike the other more common
jaw cysts and tumors (Neville et al., 2002; Avinash et
al., 2010). Odontogenic keratocysts may be found in a
wide range of patients who range in age from infancy
to old age. KCOTs are twice more frequent in the
mandible than in the maxilla (Scartezini et al., 2012)
and mandible is occupied in 60% to 80% of cases.
.
Radiographically, OKCs appear as well-defined
radiolucencies, which can be either unilocular or
multilocular and they may appear as small or large,
round or ovoid radiolucent lesions, often with
scalloped, multilocular, distinct sclerotic margins. This
type of cyst may occur in conjunction with an
impacted tooth as has been reported in 25 to 40% of
cases; in such instances, the radiographic features
suggesting more towards a diagnosis of dentigerous
cyst while smaller cysts makes the diagnosis more
dilemmatic (Neville et al., 2002; Hiremath et al., 2011;
Scartezini et al., 2012; ).
