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heat-shock/chaperone protein. These properties may be a
medicinal benefit, e.g., in wound healing, blood
coagulation and fibrinolysis.
Conclusion
The potential of PIs is quite evident and using PIs for
developing transgenics can give durable resistance
than using
Bt
genes alone. As such, the inhibitors can
probably act not only as self-sufficient protective
proteins, but can also protect other recombinant
proteins from the deleterious effects of proteolytic
enzymes. Apart from this, medicinal properties of
proteinase inhibitors are being explored. Much
importance and awareness are required to implement
the same for health benefits in it’s the most available
forms throughout.
Acknowledgements
CB is grateful to the authors for providing necessary support.
Reference
Abdel-Meguid M., Von Der Helm K., Korant B.D., and Cheronis J.C., 2000,
Proteases as targets for therapy, Springer, Berlin, Germany
Agrawal G.K., Jwa N.S., and Rakwal R., 2000, A novel rice (
Oryza sativa
L.)
acidic
PR1
gene highly responsive to cut, phytohormones, and protein
phosphatase inhibitors, Biochem. Biophys. Res. Commun., 274(1):
157-165 http://dx.doi.org/10.1006/bbrc.2000.3114 PMid:10903912
Alborn T., Turlings T.C.J., Jones T.H., Stenhagen G., Loughrin J.H., and
Tumlinson J.H., 1997, An elicitor of plant volatiles from beet
armyworm oral secretion, Science, 276(5314): 945-949 http://dx.doi.
org/10.1126/science.276.5314.945
Alonso M., Hidalgo J., Hendricks L., and Velasco A., 1996, Degradation of
aggrecan precursors within a specialized subcompartment of the
chicken chondrocyte endoplasmic reticulum, Biochem. J., 316(Pt 2):
487-495 PMid:8687392 PMCid:1217376
Alvarez-Alfageme F., Maharramov J., Carrillo L., Vandenabeele S.,
Vercammen D., van Breusegem F., Smagghe G., 2011, Potential use of
a serpin from Arabidopsis for pest control, PLoS One, 6(5): e20278
http://dx.doi.org/10.1371/journal.pone.0020278 PMid:21655276 PMC
id: 3104999
Aoki H., Akaike T., Abe K., Kuroda M., Arai S., Okamura R., Negi A., and
Maeda H., 1995, Antiviral effect of oryzacystatin, a proteinase inhibitor
in rice, against herpes simplex virus type 1
in vitro
and
in vivo
,
Antimicrobial Agents and Chemotherapy, 39(4): 846-849 http://dx.doi.
org/10.1128/AAC.39.4.846 PMid:7785982 PMCid:162640
Applebaum S.W., 1985, Biochemistry of Digestion, In: Kerkot G.A., and
Gilbert L.I. (eds.), Comprehensive insect physiology; Biochemostry
and Pharmacology, Pergamon Press, Oxford, UK, pp.279-311
Atkinson H.J., Urwin P.E., and Mcpherson M.J., 2003, Engineering plants
for nematode resistance, Annual Review of Phytopathol, 41: 615-639
http://dx.doi.org/10.1146/annurev.phyto.41.052002.095737 PMid:1273
0388
Bhattacharjee C., Bhavani P., Mohan M.N., and Prasad D.T., 2006,
Purification and characterization of trypsin proteinase inhibitor from
Cocculus hirsutus
, Plant and Animal Genomes XIV Conference, San
Diego, 14~16, Januarary, CA, USA, pp. 927
Bhattacharjee C., Manjunath N.H., and Prasad D.T., 2009, Purification of a
trypsin inhibitor from
Cocculus hirsutus
and identification of its
biological activity, Journal of Crop Science and Biotechnology, 12(4):
253-256 http://dx.doi.org/10.1007/s12892-009-0094-8
Bhattacharjee C., and Prasad D.T., 2005, Purification and Characterization
of trypsin proteinase inhibitor from
Cocculus hirsutus
and evaluation
for antifungal activity, In: DAE BRNS Life Sciences symposium
(LSS2005) on Molecular biology of Stress response and its application,
19~21, December, Bhava Atomic Research Centre, Bombay, India
Bhavani P., Bhattacherjee C., and Prasad D.T., 2007, Bioevaluation of
Subabul (
Leucaena leucocephala
) proteinase inhibitors on
Helicoverpa
armigera
, Arthropod-Plant Interactions, 1(4): 255-261 http://dx.doi.org
/ 10.1007/s11829-007-9020-5
Birk Y., 1993, Protease inhibitors of plant origin and role of protease
inhibitors in human nutrition, In: Troll W., Kennedy A.R. (eds.),
Protease inhibitors as cancer chemopreventive agents, Plenum Press,
New York, USA, pp.97-106 http://dx.doi.org/10.1007/978-1-4615
-2882-1_5
Birk Y., 2003, Plant protease inhibitors: significance in nutrition, plant
protection, cancer prevention and genetic engineering, Springer, Berlin,
Germany, pp.170
Borella M.A., Xu Y., Prabha T.N., Zhao Y., Narasimhan M.L., Wilson K.A.,
Nielsen S.S., Bressan R.A., and Hasegawa P.M., 1996, Different
expression of soybean cystein proteinase inhibitor genes during
development and response to wounding and methyl jasmonate, Plant
physiol., 112(3): 1201-1210 http://dx.doi.org/10.1104/pp.112.3.1201
PMid:8938418 PMCid:158047
Bryant J., Green T.R., Gurusaddaiah T., and Ryan C.A., 1976, Proteinase
inhibitor II from potatoes: isolation and characterization of its promoter
components, Biochem., 15(16): 3418-3424 http://dx.doi.org/10.1021/
bi00661a004 PMid:821519
Brzin J., and Kidric M., 1995, Proteinases and their inhibitors in plants: role
in normal growth and in response to various stress conditions,
Biotechnol. Genet. Eng. Rev., 13: 420- 467
Cai D.G., Thurau T., Tian Y.Y., Lange T., Yeh K.W., and Jung C., 2003,
Sporamin-mediated resistance to beet cyst nematodes (
Heterodera
schachtii
Schm.) is dependent on trypsin inhibitory activity in sugar
beet (
Beta vulgaris
L.) hairy roots, Plant Mol. Biol., 51(6): 839-849
http://dx.doi.org/10.1023/A:1023089017906 PMid:12777044
Chiche L., Heitz A., Gelly J.C., Gracy J., Chau P.T., Ha P.T., Hernandez J.F.
and LE-Nguyen D., 2004, Squash inhibitors: from structural motifs to
macrocyclic knottins, Curr. Protein Pept. Sci., 5(5): 341-349
http://dx.doi.org/10.2174/1389203043379477 PMid:15551519
Chrispeels M.J., and Baumgartner B., 1978, Trypsin inhibitor in mung bean
cotyledons: purification, characteristics, subcellular localization, and
metabolism, Plant Physiol., 61(4): 617-623 http://dx.doi.org/10.1104/
pp.61.4.617 PMid:16660348 PMCid:1091929
Christeller J. and Laing W., 2005, Plant serine proteinase inhibitors, Protein
and Peptide Letters, 12(5): 439-447 http://dx.doi.org/10.2174/0929
866054395329 PMid:16029156
Chougule N.P., Hivrale V.K., Chhabda P.J., Giri A.P., and Kachole M.S.,
2003, Differential inhibition of
Helicoverpa armigera
gut proteinases
by proteinase inhibitors of pigeonpea (Cajanus cajan) and its wild
relatives, Phytochem., 64(3): 681-687 http://dx.doi.org/10.1016/
S0031-9422(03)00375-3
Cipollini D.F., Busch J.W., Stowe K.A., Simms E.L. and Bergelson J., 2003,
Genetic variation and relationships of constitutive and
herbivore-induced glucosinolates, trypsin inhibitors, and herbivore
resistance in
Brassica rapa
, J. Chem. Ecol., 29(2): 285-302
http://dx.doi. org/10.1023/A:1022673726325 PMid:12737259
Clemente A., Gee J.M., Johnson I.T., Mackenzie D.A., and Domoney C.,
2005, Pea (
Pisum sativum
L.) protease inhibitors from the
Bowman-Birk class influence the growth of human colorectal