International Journal of Clinical Case Reports 2017, Vol.7, No.17, 73-80
73
Research Article Open Access
Multifocal Liposarcoma: a Rare Case Report
Ragmoun Houssem
1
, Daadoucha Abdrahmen
2
, Ajili Abir
1
, Benhlima Najeh
3
1 Department of Obstetric Gynecology Ibn El Jazzar Hospital, University hospital assistant in gynecology obstetrics, Ibn El Jazzar street, Kairouan, 3100,
Tunisia
2 Department of Radiology Ibn El Jazzar Hospital, University hospital assistant in radiology, Ibn El Jazzar street, Kairouan, 3100, Tunisia
3
Department of Cardiology Ibn El Jazzar Hospital, University hospital assistant in cardiology, Ibn El Jazzar street, Kairouan, 3100, Tunisia
Corresponding author email
International Journal of Clinical Case Reports 2017, Vol.7, No.17 doi
Received: 12 Sep., 2017
Accepted: 03 Nov., 2017
Published: 08 Dec., 2017
Copyright © 2017
Ragmoun et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:
Ragmoun H., Daadoucha A., Ajili A., and Benhlima N., 2017, Multifocal liposarcoma: a rare case report, International Journal of Clinical Case Reports,
7(17): 73-80 (doi
Abstract
Soft tissue multifocal liposarcoma is a rare entity in pathology and accounts for only 1 per cent of malignant tumors of
adults. The difficulty lies in identifying whether it was multifocal liposarcoma or metastatic disease. We report in our article a case
about this rare pathology, which can present itself by a deceptive and falsely reassuring symptomatology with a rapidly fatal
evolution, by insisting on its radiological aspects which are rather characteristic.
Keywords
Liposarcoma; Multifocal; Ultrasound; CT scan; Magnetic resonance imaging (MRI)
Background
Soft tissue multifocal sarcoma is a rare clinical entity occurring in 1% of patients with limb soft tissue sarcoma
and in 4.5% of patients with liposarcoma. Multimodality is defined as the presence of sarcoma at two or more
anatomically separated sites prior to disease manifestation in sites where Soft tissue multifocal sarcoma is most
commonly characterized by metastases such as lungs.
The first reported case of multifocal sarcoma dates back to 1934, when Siegmund described a case with multiple
malignant lipomatous tumors in a 65-year-old patient in whom the first tumor was noted in the soft tissues of the
thigh. Since then, many case studies have been described and the difficulty always lies in the existence of
controversy as to whether this entity represents several separate primary tumors or is simply an unusual pattern of
metastasis.
Our patient presented multiple synchronous locations and she had as a circumstance of discovery a breast nodule.
The relevance of our case is in the clinical presentation of the disease, the particular type of liposarcoma in its
multifocal form and the richness of the iconography presented.
1 Observation
Patient KH.H, 34 years old, nulliparous nulliparous, consults for left breast nodules discovered by
self-examination with mastodynia.
In mammography, we note the presence of two breasts of comparable volume, fibro-lipomatous density type 2 of
Birads. Four dense round masses of regular contours have been found in the left breast (Figure 1).
At the echomammography, several masses of the left breast were found in the form of well circumscribed,
hypoechoic masses of great axis parallel to the skin, having a posterior reinforcement, without other detectable
anomalies.
These lesions appeared to presumably benign masses of the left breast adenofibromas and the balance was rated
ACR 3 on the left and ACR1 on the right.
