Journal of Mosquito Research 2024, Vol.14, No.1, 34-48 http://emtoscipublisher.com/index.php/jmr 47 eco-friendly mosquito control methods. This includes the introduction of more targeted microbes, the development of new biological control methods, and the integration of microbes with other environmentally friendly control methods to form a more comprehensive and efficient mosquito control strategy. As genetic engineering techniques continue to evolve, researchers are beginning to explore the regulation of mosquito-microbe interactions through genetic engineering. Future studies will also need to more comprehensively assess the feasibility and potential risks of genetically engineered mosquitoes and focus on their interactions with microorganisms to ensure that potential impacts on ecosystems and human health are fully considered. As genetic engineering technology continues to evolve, researchers have begun to explore the modulation of mosquito-microbe interactions through genetic engineering. Future research will also need to more fully assess the feasibility and potential risks of genetically engineering mosquitoes, focusing on their interactions with microorganisms to ensure that potential impacts on ecosystems and human health are adequately considered. As global climate change intensifies, there may be changes in ecosystem structure and function that could in turn affect microbial-mosquito interactions. Attention can also be paid to the response of climate change to microbe-mosquito relationships to better predict the behavioral and ecological effects of mosquitoes under different climatic conditions. Taken together, the study of microbe-mosquito behavioral relationships will continue to be a challenging but highly interesting area. 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