Journal of Mosquito Research 2024, Vol.14, No.1, 10-17 http://emtoscipublisher.com/index.php/jmr 15 predators may be reduced, thus affecting the abundance and distribution of upstream and downstream populations of organisms. Figure 4 Gene mosquito niche reassignment (Image Source: Baidu Image Library) Ecological niche redistribution may lead to changes in competitive relationships. There is resource and spatial competition between mosquitoes and other organisms, and changes in their populations and behaviors may affect other organisms with which they interact. Changes in competitive relationships may trigger changes in the populations of non-target species, thus affecting the stability of the entire ecosystem. Ecosystem stability assessment requires an integrated approach. This involves the collection and analysis of data on a number of aspects such as ecological niches, food chains, competitive relationships, etc., in order to predict possible changes and instability in ecosystems. The results of the assessment will help to develop management strategies to reduce the potential impacts of ecological niche reallocation on ecosystem stability. 3.3 Risk assessment method: combination of simulation and on-site monitoring In response to the release of gene-edited mosquitoes, it is critical to conduct a comprehensive risk assessment that includes a combination of both modeling and field monitoring approaches. Simulation methods can be used to predict the potential impacts of the release of edited mosquitoes through ecological modeling. These models can take into account factors such as mosquito interactions with other organisms, food chains and ecological niches to predict the potential impacts of editing mosquitoes on ecosystem stability. The modeling approach can provide a preliminary assessment to help identify possible risk points and key variables. Field monitoring is one of the most important tools for assessing risk. Following the release of editing mosquitoes, field monitoring allows for the collection of actual data, the validation of the accuracy of modeling predictions and the timely detection of unanticipated impacts. By monitoring the numbers, behaviors and interactions of editing mosquitoes and other biological populations, it is possible to understand whether there are abnormal changes or trends in them. Data from field monitoring will provide a real and reliable basis for assessing risks and help to identify potential problems early. A combination of modeling and field monitoring can provide a more comprehensive assessment of potential risks. Simulation methods can help to predict possible impacts and trends and provide guidance for field monitoring, helping to identify monitoring priorities and parameters. Data from field monitoring can be used to validate the accuracy of the simulation, while also revealing unanticipated situations. The combination of the two approaches can compensate for each other's shortcomings and provide more comprehensive and accurate risk assessment results. The results of the risk assessment should be fed back into the management strategy. Based on assessments from modeling and field monitoring, it is critical to develop effective management measures to mitigate potential risks. This may involve limiting the number or range of editing mosquitoes, setting up a monitoring program, and
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