International Journal of Molecular Evolution and Biodiversity 2024, Vol.14, No.3, 120-132 http://ecoevopublisher.com/index.php/ijmeb 130 and enhance cassava’s utility as a food resource. As climate change poses increasing threats to global food production, understanding the genetic basis of cassava’s adaptability becomes ever more critical. These insights empower breeders to develop varieties that can withstand environmental stresses while meeting the needs of diverse cultures and economies. As this review suggests, the future of cassava research lies in harnessing emerging technologies and fostering interdisciplinary collaborations. Such approaches will enhance our understanding of cassava’s past and present, guiding its sustainable use as a crop for the future. In conclusion, the journey of cassava from a wild species to a cornerstone of food security illustrates the power of phylogenetic research in unlocking the genetic potential of crops to address global challenges. This body of work not only contributes to our historical knowledge but also paves the way for innovations that will sustain cassava as an indispensable resource for generations to come. Acknowledgments We extend our sincere thanks to two anonymous peer reviewers for their invaluable feedback on the initial draft of this paper, whose critical evaluations and constructive suggestions have greatly contributed to the improvement of our manuscript. Funding This project was funded by the Hainan Institute of Tropical Agricultural Resources under the research contract for the project “Screening and Breeding of Cassava Resources” (Project Number H20230201). Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References An F., Chen T., Stéphanie D., Li K., Li Q., Carvalho L., Tomlins K., Li J., Gu B., and Chen S., 2016, Domestication syndrome is investigated by proteomic analysis between cultivated cassava (Manihot esculenta Crantz) and its wild relatives, PLoS ONE, 11. https://doi.org/10.1371/journal.pone.0152154 PMid:27023871 PMCid:PMC4811587 Bredeson J., Lyons J., Prochnik S., Wu G., Ha C., Edsinger-Gonzales E., Grimwood J., Schmutz J., Rabbi I., Egesi C., Nauluvula P., Lebot V., Ndunguru J., Mkamilo G., Bart R., Setter T., Gleadow R., Kulakow P., Ferguson M., Rounsley S., Rokhsar D., Rokhsar D., and Rokhsar D., 2016, Sequencing wild and cultivated cassava and related species reveals extensive interspecific hybridization and genetic diversity, Nature Biotechnology, 34: 562-570. https://doi.org/10.1038/nbt.3535 PMid:27088722 Burns A., Gleadow R., Cliff J., Zacarias A., and Cavagnaro T., 2010, Cassava: the drought, war and famine crop in a changing world, Sustainability, 2: 3572-3607. https://doi.org/10.3390/su2113572 Carvalho L., Anderson J., Mba C., and Doğramacı M., 2018, Domestication syndrome in cassava (Manihot esculenta Crantz): assessing morphological traits and differentially expressed genes associated with genetic diversity of storage root. https://doi.org/10.5772/intechopen.71348 Chen X., Lai H., Li R., Yao Y., Liu J., Yuan S., Fu S., Hu X., and Guo J., 2021, Character changes and Transcriptomic analysis of a cassava sexual Tetraploid, BMC Plant Biology, 21. https://doi.org/10.1186/s12870-021-02963-1 PMid:33874893 PMCid:PMC8056498 Daemo B., Yohannes D., Beyene T., and Abtew W., 2023, AMMI and GGE biplot analyses for Mega environment identification and selection of some high-yielding cassava genotypes for multiple environments, International Journal of Agronomy, https://doi.org/10.1155/2023/6759698 Ding Z., Zhang Y., Xiao Y., Liu F., Wang M., Zhu X., Liu P., Sun Q., Wang W., Peng M., Brutnell T., and Li P., 2016, Transcriptome response of cassava leaves under natural shade, Scientific Reports, 6. https://doi.org/10.1038/srep31673 PMid:27539510 PMCid:PMC4990974 Elias A., Rabbi I., Kulakow P., and Jannink J., 2017, Improving genomic prediction in cassava field experiments using spatial analysis, G3: Genes|Genomes|Genetics, 8: 53 - 62. https://doi.org/10.1534/g3.117.300323 PMid:29109156 PMCid:PMC5765366
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