Triticeae Genomics and Genetics, 2025, Vol.16, No.2, 72-78 http://cropscipublisher.com/index.php/tgg 77 will accelerate the discovery and utilization of superior alleles, thereby rapidly increasing wheat yields. It is also important to continue studying the different functions of TaGW2 and its interactions with other yield genes. This will further optimize breeding methods and help to breed new high-yield and stress-resistant wheat varieties. CRISPR/Cas9 targeted editing of TaGW2 is a precise, powerful, and scalable method. It not only increases grain weight and yield, but is also suitable for integration into modern breeding systems, and has great potential. Acknowledgments I appreciate Dr Xu from the Hainan Institution of Biotechnology for her assistance in references collection and discussion for this work completion. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. 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