Triticeae Genomics and Genetics, 2024, Vol.15, No.3, 137-151 http://cropscipublisher.com/index.php/tgg 143 study identified multiple disease resistance meta-QTL (MDR-MQTLs) for three types of rust diseases in wheat. By analyzing 152 individual QTL mapping studies, a total of 1,146 QTLs were retrieved, and 86 MQTLs were identified through meta-analysis (Pal et al., 2022). Among these, 71 were MDR-MQTLs, and 20 were co-located with known resistance genes. This study highlights the potential of these MQTLs in breeding programs aimed at developing varieties resistant to the three types of rust diseases. Figure 2 Distribution of 63 MQTLs on 21 wheat chromosomes (Adopted from Saini et al., 2021) Image caption: The figure presents the distribution of 63 meta-QTLs (MQTLs) across 21 wheat chromosomes. The boxes on the right of each chromosome indicate the positions of the MQTLs, with red boxes representing MQTLs validated through genome-wide association studies (GWAS). The figure only shows the flanking markers of the MQTLs for better visualization. The distribution of these MQTLs is uneven, with chromosome 5B having the highest number of MQTLs, totaling 7, while chromosomes 1D, 2A, 4A, 6D, and 7D each have only one MQTL. Of these MQTLs, 60 have been anchored to the wheat reference physical map, and 38 have been validated through GWAS. These MQTLs provide important information for the fine mapping of multi-disease resistance genes and marker-assisted breeding in wheat (Adapted from Saini et al., 2021)
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