CMB_2025v15n2

Computational Molecular Biology 2025, Vol.15, No.2, 84-90 http://bioscipublisher.com/index.php/cmb 90 Miao L., Zhou Q., Peng C., Liu Z., and Xiong L., 2019, Leonurus japonicus (Chinese motherwort), an excellent traditional medicine for obstetrical and gynecological diseases: a comprehensive overview, Biomedicine & Pharmacotherapy, 117: 109060. https://doi.org/10.1016/j.biopha.2019.109060 Rong W., Li J., Wang L., Luo S., Liang T., Qian X., Zhang X., Zhou Q., Zhu Y., and Zhu Q., 2022, Investigation of the protective mechanism of leonurine against acute myocardial ischemia by an integrated metabolomics and network pharmacology strategy, Frontiers in Cardiovascular Medicine, 9: 969553. https://doi.org/10.3389/fcvm.2022.969553 Shang X., Pan H., Wang X., He H., and Li M., 2014, Leonurus japonicus Houtt.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine, Journal of Ethnopharmacology, 152(1): 14-32. https://doi.org/10.1016/j.jep.2013.12.052 Tan Y., Xu D., Yue S., Tang Y., Guo S., Yan H., Zhang J., Zhu Z., Shi X., Chen Y., Gu Y., Ding X., Huang S., Peng G., Zhou G., and Duan J., 2020, Comparative analysis of the main active constituents from different parts of Leonurus japonicus Houtt. and from different regions in China by ultra-high performance liquid chromatography with triple quadrupole tandem mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 177: 112873. https://doi.org/10.1016/j.jpba.2019.112873 Tian Z., Liu F., Peng F., He Y., Shu H., Lin S., Chen J., Peng C., and Xiong L., 2021, New lignans from the fruits of Leonurus japonicus and their hepatoprotective activities, Bioorganic Chemistry, 115: 105252. https://doi.org/10.1016/j.bioorg.2021.105252 Wang J., Mao Y., Yu Y., Yang J., Jin B., Lin H., Tang J., Zeng W., Zhao Y., Gao W., Peters R., Guo J., Cui G., and Huang L., 2022, Diterpene synthases from Leonurus japonicus elucidate epoxy-bridge formation of spiro-labdane diterpenoids, Plant Physiology, 189(1): 99-111. https://doi.org/10.1093/plphys/kiac056 Xie Z., Nolan T., Jiang H., and Yin Y., 2019, AP2/ERF transcription factor regulatory networks in hormone and abiotic stress responses in Arabidopsis, Frontiers in Plant Science, 10: 228. https://doi.org/10.3389/fpls.2019.00228 Zhang L., Khoo C., Xiahou Z., Reddy N., Li Y., Lv J., Sun M., Fan H., and Zhang X., 2024, Antioxidant and anti-melanogenesis activities of extracts from Leonurus japonicus Houtt, Biotechnology and Genetic Engineering Reviews, 39(1): 1-22. https://doi.org/10.1080/02648725.2023.2202544 Zhang Y., Cui X., Wang W., Hou J., and Yan B., 2022, Effects of pH value on stachydrine biosynthesis of hydroponic Leonurus japonicus and its physiological mechanism, China Journal of Chinese Materia Medica, 47(20): 5502-5507. https://doi.org/10.19540/j.cnki.cjcmm.20220712.101 Zhang Y., Deng S., Qu L., An Y., Wu C., Han L., Gao X., and Wang T., 2013, Rare syringyl acylated flavonol glycosides from the aerial parts of Leonurus japonicus Houtt, Molecules, 18(3): 2967-2977. https://doi.org/10.3390/molecules18032967 Zhang Y., Wang W., Du S., Wei J., Xie J., Hou F., and Xu Y., 2007, Effects of nitrogen, phosphorus, and potassium on seedling growth and stachydrine and total alkaloid from Leonurus japonicus, Chinese Traditional and Herbal Drugs, 38(12): 1881-1884. Zhou M., and Memelink J., 2016, Jasmonate-responsive transcription factors regulating plant secondary metabolism, Biotechnology Advances, 34(4): 441-449. https://doi.org/10.1016/j.biotechadv.2016.02.004 Zhu W.D., 2024, Regulation of secondary metabolite pathways in Ganoderma lucidum under environmental stress, Medicinal Plant Research, 14(4): 223-233. https://doi.org/10.5376/mpr.2024.14.0019

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