CMB_2025v15n2

Computational Molecular Biology 2025, Vol.15, No.2, 75-83 http://bioscipublisher.com/index.php/cmb 81 Cordyceps polysaccharides do have many potential applications in the pharmaceutical and health product industries, mainly due to their various biological activities and potential health benefits. For example, it can regulate immunity, resist oxidation, and even have anti-tumor effects, making it a valuable ingredient in the development of new therapeutic agents or functional foods. As research deepens, there should be more opportunities for Cordyceps polysaccharides to be included in mainstream health products-after all, their natural sources, combined with various health benefits, will drive their practical application and make the market more accepting. Acknowledgments We would like to express our heartfelt thanks to all the teachers who have provided guidance for this study. Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Ashaolu T., 2020, Immune boosting functional foods and their mechanisms: a critical evaluation of probiotics and prebiotics, Biomedicine & Pharmacotherapy, 130: 110625. https://doi.org/10.1016/j.biopha.2020.110625 Bertocci F., Grandoni A., Fidanza M., and Berni R., 2021, A guideline for implementing a robust optimization of a complex multi-stage manufacturing process, Applied Sciences, 11(4): 1418. https://doi.org/10.3390/APP11041418 Bi S., Jing Y., Zhou Q., Hu X., Zhu J., Guo Z., Song L., and Yu R., 2018, Structural elucidation and immunostimulatory activity of a new polysaccharide from Cordyceps militaris, Food & Function, 9(1): 279-293. https://doi.org/10.1039/c7fo01147d Cai R.R., Zhao L.F., and Suo M.R., 2024, Active essence of Chrysanthemum morifolium: comprehensive study of chemical characteristics and bioactivity, Medicinal Plant Research, 14(1): 45-56. https://doi.org/10.5376/mpr.2024.14.0004 Chen S., Wang J., Dong N., Fang Q., Zhang Y., Chen C., Cui S., and Nie S., 2023, Polysaccharides from natural Cordyceps sinensis attenuated dextran sodium sulfate-induced colitis in C57BL/6J mice, Food & Function, 14(2): 720-733. https://doi.org/10.1039/d2fo02555h Cheung J., Li J., Cheung A., Zhu Y., Zheng K., Bi C., Duan R., Choi R., Lau D., Dong T., Lau B., and Tsim K., 2009, Cordysinocan, a polysaccharide isolated from cultured Cordyceps, activates immune responses in cultured T-lymphocytes and macrophages: signaling cascade and induction of cytokines, Journal of Ethnopharmacology, 124(1): 61-68. https://doi.org/10.1016/j.jep.2009.04.010 De Chernatony L., 2001, A model for strategically building brands, Journal of Brand Management, 9(1): 32-44. https://doi.org/10.1057/PALGRAVE.BM.2540050 Ding K., Wang Y., and Han C., 2023, Polysaccharide elicitors affect the yield, Polysaccharide Synthase and antibacterial activity of intracellular polysaccharides from submerged culture of Cordyceps milifaris (ascomycetes), International Journal of Medicinal Mushrooms, 25(2): 35-48. https://doi.org/10.1615/intjmedmushrooms.2022046732 Finnegan D., Tocmo R., and Loscher C., 2023, Targeted application of functional foods as immune fitness boosters in the defense against viral infection, Nutrients, 15(15): 3371. https://doi.org/10.3390/nu15153371 He S., and Liao S., 2024, Discussion on pharmaceutical process optimization and technological innovation strategy, MEDS Public Health and Preventive Medicine, 4(2): 80-85. https://doi.org/10.23977/phpm.2024.040211 Hu Y., Wu Y., Song J., Ma M., Xiao Y., and Zeng B., 2024, Advancing Cordyceps militaris industry: gene manipulation and sustainable biotechnological strategies, Bioengineering, 11(8): 783. https://doi.org/10.3390/bioengineering11080783 Hu Z., Wang J., Jin L., Zong T., Duan Y., Sun J., Zhou W., and Li G., 2022, Preparation, characterization and anti-complementary activity of three novel polysaccharides from Cordyceps militaris, Polymers, 14(21): 4636. https://doi.org/10.3390/polym14214636 Idigova L., Chaplaev H., and Mazhiev K., 2023, Promising directions for improving production using innovative achievements, In: SHS Web of Conferences, EDP Sciences, 164: 00075. https://doi.org/10.1051/shsconf/202316400075 Jiang L., Zhang G., Li Y., Shi G., and Li M., 2021, Potential application of plant-based functional foods in the development of immune boosters, Frontiers in Pharmacology, 12: 637782. https://doi.org/10.3389/fphar.2021.637782

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