Computational Molecular Biology 2025, Vol.15, No.1, 13-25 http://bioscipublisher.com/index.php/cmb 13 Review and Progress Open Access Long-Term Evaluation of the Effects of An ‘Internet Plus’ Continuous Care Platform in Chronic Disease Management Xiuli Ma, Lingling Qin, Chunyue He, Yeli Huang 1 Heart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, China 2 Nursing Department, The Sixth Medical Center,General Hospital of People’s Liberation Army, Beijing, 100048, China Corresponding author: huangyeli88@163.com Computational Molecular Biology, 2025, Vol.15, No.1 doi: 10.5376/cmb.2025.15.0002 Received: 03 Dec., 2024 Accepted: 05 Jan., 2025 Published: 26 Jan., 2025 Copyright © 2025 Ma et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Preferred citation for this article: Ma X.L., Qin L.L., He C.Y., and Huang Y.L., 2025, Long-term evaluation of the effects of an 'internet plus' continuous care platform in chronic disease management, Computational Molecular Biology, 15(1): 13-25 (doi: 10.5376/cmb.2025.15.0002) Abstract This study evaluated the long-term effects of the "Internet Plus" continuous care platform in chronic disease management, focusing on its impact on patient health outcomes and mental well-being. A pre-post intervention design was employed, recruiting 230 chronic disease patients from multiple primary care clinics. Data were collected through electronic health records, patient self-reports, and platform usage metrics. The results showed significant improvements in emergency visit frequency, hospital readmissions, symptom management, and treatment adherence among patients using the platform. The platform's monitoring and telemedicine capabilities helped patients better manage key health metrics, such as blood pressure and blood glucose levels, thereby enhancing self-efficacy. Additionally, its social support features and mental health resources significantly reduced patients' anxiety and loneliness, leading to an improved quality of life. This study provides an in-depth analysis of the long-term effectiveness of the ‘Internet Plus’ platform in chronic disease management, offering valuable insights for policymakers and healthcare providers. Keywords Internet Plus; Chronic disease management; Continuous care; Self-management; Telemedicine 1 Introduction The increasing prevalence of chronic diseases worldwide has created a significant demand for innovative healthcare solutions that can offer continuous, effective, and accessible management options. With the rapid advancement of digital technologies, the integration of internet-based platforms with traditional healthcare—often referred to as ‘Internet Plus’-provides a promising approach to address this need. By facilitating real-time health monitoring, promoting self-management, and enabling efficient patient-provider communication, ‘Internet Plus’ platforms present a modern approach to improve the quality of chronic disease management. This study investigates the long-term effects of a continuous care model utilizing an "Internet Plus" platform in chronic disease management. It seeks to assess its impact on health outcomes, patient satisfaction, and overall healthcare service efficiency (Liu et al., 2023). Chronic diseases such as diabetes, cardiovascular diseases, and hypertension are major contributors to global morbidity and mortality, requiring ongoing management and support. However, traditional healthcare delivery models often fall short in providing the necessary continuity of care for these long-term conditions. Digital health interventions have emerged as viable alternatives to bridge this gap, with recent studies showing that internet-based platforms can improve patient outcomes by offering continuous, personalized care (Pu and Cai, 2024). The ‘Internet Plus’ continuous care platform is an innovative approach combining traditional healthcare services with internet-enabled tools to deliver enhanced patient care. This platform typically includes features such as telemedicine consultations, digital self-management tools, and health monitoring capabilities. These digital interventions allow for improved patient engagement and enable healthcare providers to track health data in real-time, thus facilitating timely interventions and reducing complications associated with chronic diseases. For instance, studies indicate that platforms with data-sharing capabilities and remote health monitoring can significantly improve patient quality of life and reduce the risk of hospital readmissions (Opipari-Arrigan et al., 2020). Such platforms are particularly valuable in chronic disease management, where regular monitoring and timely medical adjustments are critical. Research has shown that platforms using real-time data monitoring,
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