CMB_2024v14n5

Computational Molecular Biology 2024, Vol.14, No.5, 211-219 http://bioscipublisher.com/index.php/cmb 219 Nicora G., Vitali F., Dagliati A., Geifman N., and Bellazzi R., 2020, Integrated multi-omics analyses in oncology: a review of machine learning methods and tools, Frontiers in Oncology, 10: 1030. https://doi.org/10.3389/fonc.2020.01030 Nyholm L., Koziol A.B., Marcos S., Botnen A., Aizpurua O., Gopalakrishnan S., Limborg M., Gilbert M., and Alberdi A., 2020, Holo-omics: integrated host-microbiota multi-omics for basic and applied biological research, iScience, 23(8). https://doi.org/10.1016/j.isci.2020.101414 Olivier M., Asmis R., Hawkins G.A., Howard T.D., and Cox L.A., 2019, The need for multi-omics biomarker signatures in precision medicine, International Journal of Molecular Sciences, 20(19): 4781. https://doi.org/10.3390/ijms20194781 Pazhamala L.T., Kudapa H., Weckwerth W., Millar A.H., and Varshney R.K., 2021, Systems biology for crop improvement, The Plant Genome, 14(2): e20098. https://doi.org/10.1002/tpg2.20098 Pinu F.R., Beale D.J., Paten A.M., Kouremenos K., Swarup S., Schirra H., and Wishart D., 2019, Systems biology and multi-omics integration: viewpoints from the metabolomics research community, Metabolites, 9(4): 76. https://doi.org/10.3390/metabo9040076 Raufaste-Cazavieille V., Santiago R., and Droit A., 2022, Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology, Frontiers in Molecular Biosciences, 9: 962743. https://doi.org/10.3389/fmolb.2022.962743 Reel P.S., Reel S., Pearson E., Trucco E., and Jefferson E., 2021, Using machine learning approaches for multi-omics data analysis: a review, Biotechnology Advances, 49: 107739. https://doi.org/10.1016/j.biotechadv.2021.107739 Son J., Shoaie S., and Lee S., 2020, Systems Biology: a multi-omics integration approach to metabolism and the microbiome, Endocrinology and Metabolism, 35: 507-514. https://doi.org/10.3803/EnM.2020.303 Suravajhala P., Kogelman L.J.A., and Kadarmideen H.N., 2016, Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production health and welfare, Genetics Selection Evolution, 48: 1-14. https://doi.org/10.1186/s12711-016-0217-x Veenstra T.D., 2020, Omics in systems biology: current progress and future outlook, Proteomics, 21(3-4): 2000235. https://doi.org/10.1002/pmic.202000235 Vlachavas E.I., Bohn J., Ückert F., and Nürnberg S., 2021, A detailed catalogue of multi-omics methodologies for identification of putative biomarkers and causal molecular networks in translational cancer research, International Journal of Molecular Sciences, 22(6): 2822. https://doi.org/10.3390/ijms22062822 Wörheide M.A., Krumsiek J., Kastenmüller G., and Arnold M., 2021, Multi-omics integration in biomedical research-A metabolomics-centric review, Analytica Chimica Acta, 1141: 144-162. https://doi.org/10.1016/j.aca.2020.10.038 Xiang H., and Wu Z.Q., 2024 Pathogenic mechanisms of marine pathogens and outbreak dynamics, Molecular Pathogens, 15(1): 17-29. https://doi.org/10.5376/mp.2024.15.0003 Yang Y., Saand M.A., Huang L., Abdelaal W.B., Zhang J., Wu Y., Li J., Sirohi M.H., and Wang F., 2021, Applications of multi-omics technologies for crop improvement, Frontiers in Plant Science, 12: 563953. https://doi.org/10.3389/fpls.2021.563953 Zeng D.Q., Ye Z.L., Yu G.C., Wu J.N., Xiong Y., Zhou R., Qiu W.J., Huang N., Sun L., Bin J.P., Liao Y.L., Shi M., and Liao W.J., 2020, Iobr: multi-omics immuno-oncology biological research to decode tumor microenvironment and signatures, Frontiers in Immunology, 12: 687975. https://doi.org/10.1101/2020.12.14.422647 Zhang B., and Kuster B., 2019, Proteomics is not an island: multi-omics integration is the key to understanding biological systems, Molecular and Cellular Proteomics, 18: S1-S4. https://doi.org/10.1074/mcp.E119.001693 Zhao N., Guo M., Wang K., Zhang C., and Liu X., 2020, Identification of pan-cancer prognostic biomarkers through integration of multi-omics data, Frontiers in Bioengineering and Biotechnology, 8: 268. https://doi.org/10.3389/fbioe.2020.00268

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