Bioscience Methods 2026, Vol.17, No.1, 9-22 http://bioscipublisher.com/index.php/bm 13 Figure 2 Reduced early fungal growth in CRISPR-edited grape plants lacking functional VvMLO3 (Adapted from Wan et al., 2020) Moffa et al. (2025) edited VvMLO6 and VvMLO7 at the same time. The double mutants were almost immune, with only very small fungal growth. Growth and fruiting stayed normal. They also used a Cre/lox system to remove transgenic DNA, producing mildew-resistant, transgene-free plants.
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