International Journal of Aquaculture, 2024, Vol.14, No.2, 81-90 http://www.aquapublisher.com/index.php/ija 85 ammonia toxicity employed transcriptomic analysis to evaluate the expression of genes involved in ion regulation and metabolic pathways, revealing adaptive mechanisms at the molecular level (Egnew et al., 2019). Figure 1 Effects of HS diet on hepatic histopathological, inflammatory and apoptosis responses of largemouth bass at 2w and 8w (Adopted from Chen et al., 2022) Image caption: (a) Three phenotypes of hepatic histopathological examination with symptoms from light to heavy by HE staining. (b) Statistical results of liver phenotypes and glycogen accumulation.(c) Hepatic glycogen content. (d) Liver ultrastructure. Note the part of mitochondria (M), nucleus (N), endoplasmic reticulum (ER), glycogen granules (Gly) (red arrows showed) and lipid drop (LD). (e) Effects of HS diet on the transcriptional levels of hepatic pro- and anti-inflammation-related genes. (f) Effects of HS diet on the transcriptional levels of hepatic apoptosis-related genes (Adapted from Chen et al., 2022)
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