International Journal of Molecular Veterinary Research, 2024, Vol.14, No.6, 244-253 http://animalscipublisher.com/index.php/ijmvr 252 Bridging the gap between research and practical application is crucial for maximizing the benefits of genetic studies in canids. The comprehensive genomic data and resources developed through this research provide a valuable foundation for future studies and applications. For instance, the iDog database serves as an integrated platform for accessing and analyzing genetic information, which can facilitate collaboration among researchers, veterinarians, and conservationists. By leveraging these resources, stakeholders can develop more effective breeding programs, conservation strategies, and disease management plans that are informed by the latest genetic insights. Ultimately, the integration of research findings into practical applications will enhance the health and sustainability of both domestic and wild canid populations. Acknowledgments I am grateful to Dr. Luo for critically reading the manuscript and providing valuable feedback that improved the clarity of the text. We express our heartfelt gratitude to the two anonymous reviewers for their valuable comments on the manuscript. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References DeCandia A., Schrom E., Brandell E., Stahler D., and Vonholdt B., 2020, Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus), Evolutionary Applications, 14: 429-445. https://doi.org/10.1111/eva.13127 Halo J., Pendleton A., Jarosz A., Gifford R., Day M., and Kidd J., 2019, Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids, Retrovirology, 16: 1-25. https://doi.org/10.1186/s12977-019-0468-z Henson L., Songsasen N., Waddell W., Wolf K., Emmons L., González S., Freeman E., and Maldonado J., 2017, Characterization of genetic variation and basis of inflammatory bowel disease in the toll-like receptor 5 gene of the red wolf and maned wolf, Endangered Species Research, 32: 135-144. https://doi.org/10.3354/ESR00790 Kessler C., Brambilla A., Waldvogel D., Camenisch G., Biebach I., Leigh D., Grossen, C., and Croll D., 2020, A robust sequencing assay of a thousand amplicons for the high‐throughput population monitoring of Alpine ibex immunogenetics, Molecular Ecology Resources, 22: 66-85. https://doi.org/10.1111/1755-0998.13452 Koch I., Clark M., Thompson M., Deere-Machemer K., Wang J., Duarte L., Gnanadesikan G., McCoy E., Rubbi L., Stahler D., Pellegrini M., Ostrander E., Wayne R., Sinsheimer J., and Vonholdt B., 2016, The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves, Molecular Ecology, 25(8): 1838-1855. https://doi.org/10.1111/mec.13480 Liu Y., Wang L., Xu T., Guo X., Li Y., Yin T., Yang H., Hu Y., Adeola A., Sanke O., Otecko N., Wang M., Ma Y., Charles O., Sinding M., Gopalakrishnan S., Samaniego J., Hansen A., Fernandes C., Gaubert P., Budd J., Dawuda P., Rueness, E., Jiang L., Zhai W., Gilbert T., Peng M., Qi X., Wang G., and Zhang Y., 2018, Whole‐genome sequencing of African dogs provides insights into adaptations against tropical parasites, Molecular Biology and Evolution, 35: 287-298. https://doi.org/10.1093/molbev/msx258 Mallil K., Justy F., Rueness E., Dufour S., Totis T., Bloch C., Baarman J., Amroun M., and Gaubert P., 2020, Population genetics of the African wolf (Canis lupaster) across its range: first evidence of hybridization with domestic dogs in Africa, Mammalian Biology, 100: 645-658. https://doi.org/10.1007/s42991-020-00059-1 Marsden C., Vecchyo D., O’Brien D., Taylor J., Ramírez O., Vilà C., Marquès-Bonet T., Schnabel R., Wayne R., and Lohmueller K., 2015, Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs, Proceedings of the National Academy of Sciences, 113: 152-157. https://doi.org/10.1073/pnas.1512501113 Ostrander E., Wang G., Larson G., Vonholdt B., Davis B., Jagannathan V., Hitte C., Wayne R., and Zhang Y., 2019, Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health, National Science Review, 6: 810-824. https://doi.org/10.1093/nsr/nwz049 Pilot M., Moura A., Okhlopkov I., Mamaev N., Manaseryan N., Hayrapetyan V., Kopaliani N., Tsingarska E., Alagaili A., Mohammed O., Ostrander E., and Bogdanowicz W., 2021, Human‐modified canids in human‐modified landscapes: The evolutionary consequences of hybridization for grey wolves and free‐ranging domestic dogs, Evolutionary Applications, 14: 2433-2456. https://doi.org/10.1111/eva.13257 Quéméré E., Galan M., Cosson J., Klein F., Aulagnier S., Gilot‐Fromont E., Merlet J., Bonhomme M., Hewison A., and Charbonnel N., 2015, Immunogenetic heterogeneity in a widespread ungulate: the European roe deer (Capreolus capreolus), Molecular Ecology, 24(15): 3873-3887. https://doi.org/10.1111/mec.13292
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