International Journal of Molecular Veterinary Research 2024, Vol.14, No.1, 1-8 http://animalscipublisher.com/index.php/ijmvr 3 Although antiviral drugs are theoretically effective, they face various limitations in practical application. Most antiviral drugs are designed for human viruses, and their efficacy against FCV may be limited. Additionally, the high variability of FCV may lead to the rapid development of drug resistance. Therefore, while these drugs can be part of a treatment plan, their effectiveness and safety evaluation require a comprehensive assessment of individual responses and clinical presentations. As our understanding of FCV biology deepens, novel antiviral treatment strategies are under development. For instance, approaches based on RNA interference (RNAi) are being explored to specifically target and degrade viral RNA, representing a potentially more precise treatment method. Simultaneously, researchers are also attempting to develop more effective vaccines to prevent infection or alleviate symptoms. 2.2 Supportive therapy FCV infection in cats often accompanies reduced appetite and dehydration symptoms. Therefore, proper nutrition and fluid support are crucial components of treatment. Nutritional support should include high-quality proteins, sufficient calorie intake, and essential vitamins and minerals. Regarding fluid therapy, intravenous or subcutaneous fluid administration may be necessary based on the specific condition of the affected cat to correct dehydration and maintain electrolyte balance. FCV infection commonly leads to painful symptoms such as oral ulcers in cats. Appropriate pain relief measures, such as the use of opioid medications or non-steroidal anti-inflammatory drugs (NSAIDs), can significantly improve the cat's comfort (Figure 1). However, it is essential to note that the use of these drugs must be under veterinary guidance to avoid adverse reactions. Figure 1 Oral medication In the treatment of FCV, immunomodulators also play a significant supportive role (Kulenkova et al., 2020). For example, interferons can enhance the host immune system's response to the virus. Additionally, some immune boosters like L-lysine are believed to contribute to managing FCV infections. However, the long-term efficacy and side effects of these drugs require further clinical research for clarification. 2.3 Treatment strategies in special cases For cats with chronic FCV infection, a comprehensive and long-term treatment plan is necessary. This may include regular clinical monitoring, personalized drug treatment plans, and strict hygiene control measures. The key to long-term management lies in regularly assessing changes in the cat's condition and adjusting the treatment plan accordingly.
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