International Journal of Molecular Veterinary Research 2024, Vol.14, No.1, 9-16 http://animalscipublisher.com/index.php/ijmvr 9 Research Report Open Access Enhancing Dairy Cow Milk Fat Synthesis Genes with CRISPR-Cas9 Technology to Increase Dairy Product Yield BoYang Qingyun Environmental Technology Co., Ltd, Shangyu, 312300, Zhejiang, China Corresponding author email: 1624454379@qq.com International Journal of Molecular Veterinary Research, 2024, Vol.14, No.1 doi: 10.5376/ijmvr.2024.14.0002 Received: 09 Nov., 2023 Accepted: 20 Dec., 2023 Published: 15 Jan., 2024 Copyright © 2024 Yang, This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Preferred citation for this article: Yang B., 2024, Enhancing dairy cow milk fat synthesis genes with CRISPR-Cas9 technology to increase dairy product yield, International Journal of Molecular Veterinary Research, 14(1): 9-16 (doi: 10.5376/ijmvr.2024.14.0002) Abstract This study explores the prospects and potential impacts of using CRISPR-Cas9 technology to improve the genes involved in milk fat synthesis in cows, aiming to increase dairy product yield. Dairy products hold a significant position in global diets, making it an urgent challenge to enhance dairy product production. Milk fat synthesis genes in cows play a crucial role in both the quality and quantity of dairy products. CRISPR-Cas9 technology, as an efficient and precise gene editing tool, provides a powerful instrument for improving cow genetics. By precisely editing genes related to milk fat synthesis, it is possible to enhance the milk fat synthesis capacity of cows, thereby increasing dairy product yields. Gene-edited cows also have the potential to improve milk fat quality, reduce environmental impact, enhance food safety, and bolster the sustainability of the dairy industry. However, gene editing raises ethical and legal concerns that require careful consideration. Ensuring safety and ethical compliance is a key challenge in future research and applications. In summary, the prospects for using CRISPR-Cas9 technology to improve cow milk fat synthesis genes are promising and have the potential to make significant contributions to meeting the growing global demand for dairy products. Keywords CRISPR-Cas9 technology; Cow; Milk fat synthesis; Dairy product yield; Gene editing Dairy products have long been a crucial part of human diet, offering rich nutritional value and delightful flavors. The dairy industry holds significant economic and social importance globally, providing not only high-quality proteins, fats, and vitamins to humans but also generating employment and economic opportunities for rural communities and agricultural economies, effectively supporting the sustainable development of rural society. However, the dairy industry faces growing demands, necessitating continuous improvement in both the quantity and quality of dairy products to meet global market needs. Lipid synthesis plays a vital role in dairy production, influencing not only the fat content but also the taste and texture of dairy products (Petitclerc et al., 2000). The regulation of lipid synthesis involves various factors such as diet, genetics, and environment. Nevertheless, the fundamental regulatory mechanism lies in gene control, where the genes related to lipid synthesis in cows play a crucial role. Therefore, enhancing the lipid synthesis genes in cows holds the potential to enhance dairy product yield and quality. CRISPR-Cas9 technology stands as a powerful gene-editing tool, widely applied in fields such as medicine, agriculture, and biological research, providing unprecedented tools and opportunities for gene editing. In the medical field, it has been used to treat various genetic diseases, including cancer (Ma et al., 2023). In the field of agriculture, CRISPR-Cas9 technology has successfully been employed to improve plant varieties, enhancing resistance, yield, and quality (Hou et al., 2023). Despite the critical role of lipid synthesis in the dairy industry, the regulatory mechanisms of lipid synthesis remain not fully understood. This uncertainty hinders researchers from effectively improving the lipid synthesis process in cows. In the rapidly evolving dairy market, this slow progress is no longer practical. Therefore, the rapid and precise improvement of lipid synthesis genes in cows has become a significant issue. The emergence of gene-editing technology brings new opportunities to address this problem. Through CRISPR-Cas9 technology, researchers have the potential to quickly and accurately improve the lipid synthesis genes in cows, thereby enhancing the yield and quality of dairy products. The application of this technology in cow breeding holds immense potential, but whether it can successfully achieve this goal and whether it can have a positive impact on the dairy industry still requires in-depth research and validation.
RkJQdWJsaXNoZXIy MjQ4ODYzNA==