International Journal of Molecular Veterinary Research 2024, Vol.14, No.1, 1-8 http://animalscipublisher.com/index.php/ijmvr 7 5.8 Insights into existing treatment strategies from the case Kangkang's case provides valuable practical experience for the treatment of FCV infections. It serves as a crucial reference for similar cases in the future, particularly in the application of comprehensive treatment strategies, the design of individualized treatment plans, and the management of preventing secondary infections. Additionally, this case highlights the importance of communication between veterinarians and pet owners to ensure the smooth implementation of treatment plans and timely tracking of the pet's condition. 6Summary Feline calicivirus (FCV), as a common yet complex viral disease in cats, poses multiple challenges in its treatment and management. The widespread use of antiviral drugs has led to an increasing resistance of FCV to these medications. Current vaccines do not provide complete prevention against all FCV strains, and their effectiveness against certain variants is limited (Zheng et al., 2022). The high variability of FCV complicates treatment and prevention strategies. In multi-cat environments, managing virus transmission, reducing stress, and minimizing conflicts present additional challenges. Insufficient awareness among pet owners about FCV may result in improper disease management and treatment failures. Despite the numerous challenges in treatment, technological advancements have introduced new therapeutic strategies and research directions for FCV. The development of gene editing technologies such as CRISPR offers possibilities for precise targeting and repairing of viral genes. Future researchers can explore novel antiviral drugs, especially those targeting FCV-specific mechanisms, to overcome existing drug resistance. Developing broader and more effective vaccines, particularly those capable of addressing various mutant strains, is essential (Lu et al., 2018). Researching new immunomodulatory methods to enhance host immune responses and resistance to FCV is also crucial. Creating comprehensive treatment strategies that integrate drug therapy, immune modulation, and optimized management measures is an avenue for exploration. In the future, with the collaboration of technology and interdisciplinary efforts, the development and utilization of integrated health management systems seem promising. Researchers can explore the development of intelligent health monitoring tools, such as wearable devices, for real-time monitoring of a cat's health. Utilizing big data and artificial intelligence, personalized treatment and management plans can be formulated for each cat. Establishing a comprehensive platform for pet health education can enhance pet owners' disease awareness and management skills. Promoting collaboration among veterinarians, researchers, and technology developers will collectively drive the advancement of FCV treatment and prevention technologies. In conclusion, although the current treatment and management of FCV face various challenges, there is reason to anticipate more effective control and treatment of this disease in the future, thanks to the progress in science and technology and the deepening collaboration across multiple disciplines. References Bergmann M., Speck S., Rieger A., Truyen U., and Hartmann K., 2019, Antibody response to feline calicivirus vaccination in healthy adult cats, Viruses, 11(8): 702. https://doi.org/10.3390/v11080702 PMid:31370359 PMCid:PMC6723298 Dávila I., Domínguez-Ortega J., Navarro-Pulido A., Alonso A., Antolin-Amerigo D., González-Mancebo E., Martín-García C., Núñez-Acevedo B., Prior N., Reche M., Rosado A., Ruiz-Hornillos J., Sánchez M.C., and Torrecillas M., 2018, Consensus document on dog and cat allergy, Allergy, 73(6): 1206-1222. https://doi.org/10.1111/all.13391 PMid:29318625 Gao C.X., Chen B.J., Mi J., Han J.J., Lian S.C., Ma W.R., 2022, Epidemiological investigation and analysis of feline calicivirus in Xi’an, Chinese Journal of Veterinary Medicine, 58(3): 101-105. Gui Y.P., Liu J., Bai Y.L., Wang J., and Zhao H.J., 2023, Research progress on the characteristics of virulent systemic feline calicivirus, Chinese Journal of Virology, 39(4): 1093-1098. Guo Y.B., Liu H.K., Wang Q, Yi S.S., Niu J.T., Li D.L., Cui Z.D., Wang K., Shao H.Z., and Hu G.X., 2022, Assessment of the protective efficacy of a feline calicivirus inactivated vaccine using in vivo FCV CH-JL2 infection, Pak. Vet. J., 42(3): 328-333.
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