International Journal of Clinical Case Reports 2015, Vol.5, No. 43, 1-4
4
(Singh et al., 2010). Immunohistochemical profile
studies indicate that the proliferating cells are of
myofibroblastic origin. Studies show CD68 positive
histiocytic component intermingling with lymphocytes
and plasma cells suggesting the existence of a reactive
phenomenon (Chhina et al., 2011). Treatment requires
a thorough/wide base surgical excision including the
involved periodontal ligament and periosteum to
prevent the recurrence of the lesion, as a high
recurrence rate of 7-20% has been reported (Nazareth
et al., 2011) thereby, mandating a regular follow-up.
Recurrence probably occurs due to the incomplete
removal of lesion, repeated injury and/or persistence
of local irritants. The average time interval for the first
recurrence is 12 months (Jain and Deepa, 2010).
Conclusion
POF is a slowly progressing lesion, with limited
growth. Many cases progress for prolonged periods
before patients seek treatment because of the lack of
symptoms associated with the lesion. Thorough
radiographic and histological examination must be
done, for a proper diagnosis and management of the
lesion, as it is difficult clinically to differentiate
between the various gingival lesions that are bound to
have varying aetiologies and require different treatment
modalities for their cure.
References
Bhaskar S.N., and Jacoway J.R., 1966, Peripheral fibroma and peripheral
fibroma with calcification: Report of 376 cases, J. Am. Dent. Assoc.,
73: 1312-1320
Chhina S., Rathore A.S., and Ahuja P., 2011, Peripheral ossifying fibroma of
gingiva: A case report, International Journal of Case Reports and
Images, 2: 21-24
Farquhar T.R.N., MacLellan J., Dyment H., and Anderson R.D., 2008,
Peripheral Ossifying Fibroma: A Case Report, J. Can. Dent. Assoc., 74:
809-812
Jain A., and Deepa D., 2010, Recurrence of Peripheral Ossifying Fibroma: A
Case Report, People’s Journal of Scientific Research, 3: 23-25
Keluskar V., Byakodi R., and Shah N., 2008, Peripheral Ossifying Fibroma,
Journal of Indian Academy of Oral Medicine and Radiology, 20: 54-56
Kendrick F., and Waggoner W.F., 1996, Managing a peripheral ossifying
fibroma, J. Dent. Child., 63: 135-138
Kenney J.N., Kaugars G.E., and Abbey L.M., 1989, Comparison between
the peripheral ossifying fibroma and peripheral odontogenic fibroma, J.
Oral Maxillofac Surg., 47: 378-382
Kumar S.K., Ram S., Jorgensen M.G., Shuler C.F., and Sedghizadeh P.P.,
2009, Multicentric peripheral ossifying fibroma: A case Report, Journal
of Oral Sciences, 51: 151-154
Mesquita R.A., Orsini S.C., Sousa M., and Araujo N.S., 1998, Proliferative
activity in peripheral ossifying fibroma and ossifying fibroma, J. Oral
Pathol. Med., 27: 64-67
Nazareth B., Arya H., Ansari S., and Arora R., 2011, Peripheral ossifying
fibroma: A clinical report, Int. J. Odontostomat, 5: 153-156
Neville B.W., Damm D.D., Allen C.M., and Bouquot J.E., 2002, Soft tissue
tumours (chapter12), In: Text book of Oral and Maxillofacial Pathology,
2nd Edn., Saunders, Philadelphia, 451-452
Singh A.P., Raju M.S., and Mittal M., 2010, Peripheral ossifying fibroma: A
case report, Journal of Nepal Dental Association, 11: 70-72
Moon W.J., Choi S.Y., Chung E.C., Kwon K.H., and Chae S.W., 2007,
Peripheral ossifying fibroma in the oral cavity: CT and MR findings,
Dentomaxillofacial Radiology, 36: 180-182
