International Journal of Clinical Case Reports, 2016, Vol.6, No.15, 1-9
1
Research Report
Open Access
Peripheral Ossifying Fibroma: Case Report and a Mini-review
Kaustubh P Patil
1
, Vinayak D Kanakdande
2
, Ketki P Kalele
3
, Rutuparna Sasane
4
, Sonali Deshmukh
3
, Abhisheksingh Nayyar
5
1 Department of Periodontics and Oral Implantology, Dental College and Hospital, Maharashtra, India
2 Department of Periodontics and Oral Implantology, Nanded Rural Dental College and Research Centre, Maharashtra, India
3 Department of Oral and Maxillofacial Pathology and Microbiology, V.Y.W.S Dental College and Hospital, Maharashtra, India
4 Department of Prosthodontics, Terna Dental College and Hospital, Navi Mumbai, Maharashtra, India
5 Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Maharashtra, India
Corresponding author email:
International Journal of Clinical Case Reports, 2016, Vol.6, No.15, doi:
Received: 11 Apr., 2016
Accepted: 20 May, 2016
Published: 26 May, 2016
Copyright © 2016 This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use,
distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:
Kaustubh P.P., Vinayak D.K., Ketki P.K., Rutuparna S., Sonali D., and Abhisheksingh N., 2016, Peripheral Ossifying Fibroma: Case Report and a Mini-review,
International Journal of Clinical Case Reports, 6(15): 1-9 (doi:
)
Abstract
Peripheral ossifying fibroma (POF) occurs as a gingival overgrowth. The purpose of this article is to present a case of POF,
briefly reviewing the current literature on this condition and emphasize the importance of inclusion of this lesion into list of all the
pathologies, specially the gingival overgrowths. A case report of peripheral ossifying fibroma (POF) is reported in young adolescent which
comprises the growth that occurred in the mandibular anterior region with displacement of anterior teeth, its satisfactory management and
literature review. POF represents a reactive benign lesion of connective tissue and is not the soft tissue counterpart of ossifying fibroma and
is also not related to peripheral odontogenic fibroma. Careful clinical examination and histopathology findings should be correlated to
conclude the final diagnosis. Treatment consists of surgical excision with periodic follow-ups to observe any recurrence.
Keywords
Peripheral ossifying fibroma; Gingival overgrowth; Fibroma; Granuloma; Fibroblast; Osteoid tissue
1 Introduction
Reactive lesions of the gingiva are very common. Peripheral ossifying fibroma belongs to the spectrum of reactive
gingival hyperplasias (It occurs as a gingival overgrowth in response to local irritants. The pathogenesis of this
lesion although is much under controversy (Patil et al., 2014). Other terms used in reference to POF are peripheral
cementifying fibroma, peripheral fibroma with cementogenesis and peripheral fibroma with osteogenesis,
peripheral fibroma with calcification, calcified or ossified fibrous epulis and calcified fibroblastic granuloma
(Kale et al., 2014). POF was first reported by Shepherd in 1844 as alveolar exostosis. Eversol and Robin (1972)
later coined the term peripheral ossifying fibroma (Reddy et al., 2011). It occurs in the younger age groups with a
female preponderance. It has a predilection for maxillary arch and most of them occur in the incisor cuspid region
(Mohiuddin et al., 2013). POF constitutes about 3.1% of all the oral tumors and about 9.6% of all the gingival
lesions (Mishra et al., 2011). Although POF represents benign clinical behavior, the recurrence rate can reach up
to 20% (Kale et al., 2014). This makes this entity worth discussing. The purpose of this article is to present a case
of POF, briefly reviewing the current literature on this condition and emphasize the importance of inclusion of this
lesion into the list of all pathologies, specially the gingival overgrowths.
2 Case Report
A 21 year old male patient visited a private dental practitioner with a chief complaint of swelling of gums in lower
left front tooth region of jaw which interfered during eating since 5 months. Patient noticed a small swelling in
relation to interdental papilla in 31, 32 region which gradually increased over a period of 5 months. There used to
be occasional bleeding on brushing and during mastication which stopped on its own within few minutes. The
swelling was painless, but interfered during mastication. Also, the patient noticed spacing between 31 and 32 due
to the same and this gradually increased in the last 5 months. On intra-oral examination, a 1.5 x 1 x 0.5 cm,
pedunculated, roughly ovoid, reddish pink, soft, nodular and non-tender gingival overgrowth was seen between 31
and 32 which extended from the interdental papilla to the attached gingiva (figure 1 a, figure 1 b).
