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Computational Molecular Biology 2015, Vol. 5, No. 2, 1-4
http://cmb.biopublisher.ca
4
knowledge about LncRNA molecular mechanism exist
limitations and lots of difficulties. As discussed above,
several lncRNAs have been implicated in breast
cancer, and we are confident in that further studies on
these lncRNAs could lead to new therapeutic
advances for diagnosis and treatment for breast cancer.
Acknowledgments
This work was supported by the Ministry of Education of the
People’s Republic of China (grants 20122307120034),
Heilongjiang Province of Science and Technology (grants
D201273), and Harbin Science and Technology Bureau (grants
2012RFQS064).
References
Balik V, Srovnal J, Sulla I, et al., 2013, MEG3: a novel long noncoding
potentially tumour-suppressing RNA in meningiomas. Neurooncol,
112(1): 1-8.
Bhan A, Hussain I, Ansari KI, et al., 2013, Antisense transcript long
noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by
estradiol. J Mol Biol, pii: S0022-2836(13)00038-7.
DeBaun M R, Niemitz E L, McNeil D E, et al., 2002, Epigenetic alterations
of H19 and LIT1 distinguish patients with Beckwith-Wiedemann
syndrome with cancer and birth defects. Am J Hum Genet, 70(3):
604-611.
G. Chen, Z. Wang, D. Wang, et al., 2013, lncRNA disease: a database for
long-noncoding RNA-associated diseases. Nucleic Acids Res, 41:
D983–D986.
Gutschner T, Hämmerle M, Eissmann M, et al., 2013, The noncoding RNA
MALAT1 is a critical regulator of the metastasis phenotype of lung
cancer cells. Cancer Res, 73(3): 1182-1189.
Harrow J, Frankish A, Gonzalez J M, et al., 2012, GENCODE: the reference
human genome annotation for the ENCODE Project. Genome Res, 22:
1760-1774.
J. Zhou, Y. Tian, J. Li, et al., 2013, MiR-206 is down-regulated in breast
cancer and inhibits cell proliferation through the up-regulation of
cyclinD2.Biochem Biophys Res. Commun, 433 (2): 207-212.
JEREMY E W, HONGJAE S, DAVID L S, 2009, Long noncoding RNAs:
functional surprises from the RNA world. Genes Dev,
23(13):1494-1504.
Kim E D, Sung S. 2012, Long noncoding RNA
unveiling hidden layer of
gene regulatory networks. Trends Plant Sci, 17(1): 16-21.
Lv et al., 2014, Genetics and epigenetics in human cancer, Cancer Genetics
and Epigenetics, Vol.2, No.1 1-14
doi: 10.5376/cge.2014.02.0001
M. Muthuswami, V. Ramesh, S. Banerjee, et al., 2013, Breast tumors with
elevated expression of 1q candidate genes confer poor clinical outcome
and sensitivity to Ras/PI3K inhibition. PLoS ONE, 8(10):e77553.
Novikova I V, Hennelly S P, Sanbonmatsu K Y, 2012, Structural architecture
of the human long non-coding RNA, steroid receptor RNA activator.
Nucleic Acids Res, 40(11): 5034-5051.
Orom U A, Shiekhattar R
2011, Long non-coding RNAs and
enhancers
Curr OpinGenet Dev, 21( 2) :194-198
Silva JM, Boczek NJ, Berres MW, et al., 2011, LSINCT5 is over expressed
in breast and ovarian cancer and affects cellular proliferation [J]. RNA
Biol, 8(3): 496-505.
Shore A N, Herschkowitz J I, Rosen J M, 2012, Noncoding RNAs involved
in mammary gland developmentand tumorigenesis: there's a long way
to go. Mammary Gland Biol Neoplasia, 17: 43-58.
Wang Pengjun
Ren Zhongqiao
Sun Piyun, 2012, Over expression of the
long non -coding RNAMEG3 impairs in vitro glioma cell proliferation.
J Cell Biochem, Jan10,doi: 10
1002/jcb.24055
Wenzhu Lou, Xueyan Sun, Longzhu Li, et al.,2011, Anticancer effects of
histone deacetylase inhibitors. Chinese Journal of Cell Biology, 33(9):
1045-52.
Zhang X, Tworoger S S, Eliassen A H, et al., 2013, Postmenopausal plasma
sex hormone levels and breast cancer risk over 20 years of follow-up.
Breast Cancer Res Treat, 137(3):883-892.
Zhang, 2013, Cancer research advantaged in genetics and epigenetics
progres, Cancer Genetics and Epigenetics, Vol.1, No.1 1-2
doi: 10.5376/cge.2013.01.001
Zhang et al., 2014, The Present Situation and Prospect for Gene Therapy of
Breast Cancer, Cancer Genetics and Epigenetics, Vol.2, No.2 1-8
doi: 10.5376/cge.2014.02.002